Medicine
Semaglutide: what to keep track of day to day
Quick answer
Injectable semaglutide is taken once a week and has a half-life of about 7 days. In the U.S. it comes as Ozempic® and Wegovy® pens, and as daily pills (Rybelsus® and the Wegovy® pill).
What to know
- Half-life of about 1 week; levels peak 1 to 3 days after a shot.
- Side effects listed most often on the label: nausea, diarrhea, constipation, vomiting and belly pain. They're more common at the start and after a dose increase.
- Worth tracking: your shot day and injection site, protein, water, fiber, how you feel on each day after your shot, and your weekly weight.
- On hormone therapy too? Logging both in one place helps your doctor see the full picture.
Tools and guides
Protein · Water · Fiber · Nausea · Constipation
Ozempic®, Wegovy® and Rybelsus® are trademarks of Novo Nordisk. Leve is independent and not affiliated with Novo Nordisk; brand names appear only to help you identify your treatment.
Limits
- Your dose and any dose change are decided by your doctor.
- Compounded semaglutide is not FDA-approved: check where it comes from with your doctor and pharmacist.
- This page is for information only. It doesn't replace the prescribing information or your doctor.
Sources
- FDA prescribing information for Ozempic®, Wegovy® and Rybelsus® (semaglutide).
- FDA: concerns with unapproved GLP-1 drugs used for weight loss.
Reviewed on November 7, 2026. General information, pending review by a health professional. Leve doesn't replace your doctor's advice.
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